Aplastic Anemia
Introduction of anemia :
Is anemia In rare cases, but in very serious. And giddy different ages. And speaking as a result of the failure of bone marrow in the production of blood cells different.
Containing blood on a variety of types of blood cells: red blood cells white blood cells and platelets. And every type of cell has an important role the human body. Red blood cells which carry oxygen and white blood cells attack any infection enter the body, whether bacteria or viral or parasitic infections and blood platelets help blood to clot in the case of the wound and bleeding.
And in the case of anemia no aplastic anemia depends bone marrow for the production of blood cells new and this means a lack of oxygen, who arrives in the body and increase the risk of infection, and also the lack of control of bleeding when it occurs.
And there are several ways for treatment, treatment pharmacological blood transfusion and transplantation of bone marrow.
The cause of anemia
Cavity contains many of the bones of the body to foam material red colour called bone marrow and bone marrow to posts in an extremely important it contains cells called stem cells, which is considered initial cells to manufacture the rest of the blood cells (red blood cells white blood cells blood platelets). will involve the production of blood cells in various bone marrow to enter into the bloodstream.
Needs bone marrow to continue to produce blood cells new to replace old cells. Each type of blood cells to age live and die after and needs to be compensation rather than new cells. For example, red blood cells live for 120 on blood platelets 7 days and most of white blood cells live one day or less. And in cases natural based bone marrow to provide the necessary preparation of blood cells. In the case of anemia no aplastic anemia happens the destruction of the bone marrow, causing a shortage of blood cells that are produced.
And summarized the reasons for the destruction of bone marrow in the following:
1. Exposure to high doses of radiation) during radiotherapy or chemotherapy in cases of the treatment of diseases of cancer tumors. Remedies are chemical or radiological destroy cancerous cells and does not distinguish between them and between the cells initial the bone marrow upholds also destroyed, causing anaemia cases no aplastic anemia.
2. Exposure to toxic chemicals.
3. The use of some medicines such as some medicine to treat rheumatoid and some types of antibiotics.
4. An imbalance in the immune system.
5. Hereditary factors.
6. The reasons for the unknown. sometimes occur the incidence of anemia no aplastic anemia for unknown reasons and called the poorest no blood aplastic anemia unknown reason Idiopathic aplastic anemia.
The symptoms and diagnosis of anemia:
Produce anemia no aplastic anemia from a lack of one or more of blood cells. And speaking anemia either suddenly or progressively within weeks or months. And without treatment may develop the disease and threatens the life of the patient.
And the symptoms include the following:
The low number of red blood cells lead to anemia, causing:
1.The general feeling unwell.
2. Dizziness and headaches.
3. Shortness of breath when effort.
4. The speed of heart attacks. And is due to the fact that in the event of a shortage of red blood cells, the heart more pumped blood so he can compensate for the lack of red blood cells and the delivery of oxygen to all parts of the body.
5. Fading skin colour.
The low number of white blood cells lead to
* Injuries: repeated infected either viral and bacterial or otherwise.
The low number of blood platelets lead to:
1. The emergence of bruises in any part of the body without any apparent reason.
2. The emergence of spots or small granules red under the skin.
3. Bleeding nose and gum bleeding.
4. To increase the duration of bleeding when wound infection.
Diagnosis of anemia no aplastic anemia Diagnosis
diagnosed to be anemia no aplastic anemia through: Analysis of
1. Complete full blood count: shows a severe shortage in the number of red blood cells and white blood platelets.
2. A sample of bone marrow.
The treatment of anaemia
Ranging the severity of aplastic anemia the degree of simple medium or acute (strong). In acute cases of the disease there is a severe shortage in the preparation of blood cells, which exposes the patient's life at risk and need to enter the hospital immediately because the treatment in such cases would be to transplant bone marrow. Either in simple cases or medium of the disease, there is no need to hospital and is treated in the transfer of blood and the use of medicines.
The main methods of treatment in the following:
1. Blood transfusion
Most patients aplastic anemia needed to transport repeated blood. will involve the transfer of red blood cells or blood platelets or both depending on the situation of the disease. And does not consider the transfer of blood treatment final of the disease is only offset the shortage of blood cells, which is not based bone marrow for producing and therefore controlled of the symptoms of the lack of these cells.
A. Red blood cells: the transfer of red blood cells lead to a rise in the number of blood and therefore disappear symptoms of anemia and fatigue suffered by the patient. and be the choice of a donor match the same blood group with blood group the patient. And continue transferred cells in the blood of the patient for a month or more.
B. Platelets: to be a compilation of blood platelets after it had been separated from the blood of contributor in a certain way and then be given for the patient.
C. White blood cells: In view of the short age white blood cells would be difficult to transfer the patient. It is therefore the patient infection exhibition easily there is nothing in his white blood cells enough to meet any infection he is exposed to.
2. Medicines and discouraging immune system:
In some cases be the use of medicines and discouraging immune system for treatment because it may be the cause of anemia cases no aplastic anemia is a disorder the immune system shall commence in attacking cells in bone marrow. When the use of such medicines based activity by discouraging the immune system does not affect bone marrow and start bone marrow cells new blood.
For instance those medicines anti-cells anti-thymocyte globulin. Thymoglobulin acetate cyclosporine. and be used alongside medicines Corticosteroids.
3. Bone marrow stimulants:
There are some medicines lead to stimulate and the revitalization of bone marrow cells to produce new blood.
4. Bone marrow transplantation:
To be the replacement of bone marrow to patients great marrow another person unhurt (donor). Is to transplant bone marrow is the only option successful in acute cases (strong) of anemia no aplastic anemia . And the proportion of its success more than 50% of cases where the donor is not of the relatives of the patient. And when contributor of relatives of the patient is getting a chance the success of treatment between each 5 cases of the treatment of 4 cases successfully.
In finding appropriate contributor will be the work of the necessary tests to him. and have been exhausted bone marrow to patients using X-rays or chemical medicines. And then the taking of bone marrow from the donor in a manner that surgery. After that to be the introduction of bone marrow in the blood of the patient through intravenous. find themselves moving bone marrow to bone-cavity and then begins in the composition of blood cells through new 3-4 weeks.
And need transplant of bone marrow to stay in hospital for a long time with some drugs that prevent the rejection of the body of the bone marrow transferred to him.
Aplastic Anemia
اعداد
سلام جبار سلمان
مصطفى حاتم فيصل
Introduction of anemia :
Is anemia In rare cases, but in very serious. And giddy different ages. And speaking as a result of the failure of bone marrow in the production of blood cells different.
Containing blood on a variety of types of blood cells: red blood cells white blood cells and platelets. And every type of cell has an important role the human body. Red blood cells which carry oxygen and white blood cells attack any infection enter the body, whether bacteria or viral or parasitic infections and blood platelets help blood to clot in the case of the wound and bleeding.
And in the case of anemia no aplastic anemia depends bone marrow for the production of blood cells new and this means a lack of oxygen, who arrives in the body and increase the risk of infection, and also the lack of control of bleeding when it occurs.
And there are several ways for treatment, treatment pharmacological blood transfusion and transplantation of bone marrow.
The cause of anemia
Cavity contains many of the bones of the body to foam material red colour called bone marrow and bone marrow to posts in an extremely important it contains cells called stem cells, which is considered initial cells to manufacture the rest of the blood cells (red blood cells white blood cells blood platelets). will involve the production of blood cells in various bone marrow to enter into the bloodstream.
Needs bone marrow to continue to produce blood cells new to replace old cells. Each type of blood cells to age live and die after and needs to be compensation rather than new cells. For example, red blood cells live for 120 on blood platelets 7 days and most of white blood cells live one day or less. And in cases natural based bone marrow to provide the necessary preparation of blood cells. In the case of anemia no aplastic anemia happens the destruction of the bone marrow, causing a shortage of blood cells that are produced.
And summarized the reasons for the destruction of bone marrow in the following:
1. Exposure to high doses of radiation) during radiotherapy or chemotherapy in cases of the treatment of diseases of cancer tumors. Remedies are chemical or radiological destroy cancerous cells and does not distinguish between them and between the cells initial the bone marrow upholds also destroyed, causing anaemia cases no aplastic anemia.
2. Exposure to toxic chemicals.
3. The use of some medicines such as some medicine to treat rheumatoid and some types of antibiotics.
4. An imbalance in the immune system.
5. Hereditary factors.
6. The reasons for the unknown. sometimes occur the incidence of anemia no aplastic anemia for unknown reasons and called the poorest no blood aplastic anemia unknown reason Idiopathic aplastic anemia.
The symptoms and diagnosis of anemia:
Produce anemia no aplastic anemia from a lack of one or more of blood cells. And speaking anemia either suddenly or progressively within weeks or months. And without treatment may develop the disease and threatens the life of the patient.
And the symptoms include the following:
The low number of red blood cells lead to anemia, causing:
1.The general feeling unwell.
2. Dizziness and headaches.
3. Shortness of breath when effort.
4. The speed of heart attacks. And is due to the fact that in the event of a shortage of red blood cells, the heart more pumped blood so he can compensate for the lack of red blood cells and the delivery of oxygen to all parts of the body.
5. Fading skin colour.
The low number of white blood cells lead to
* Injuries: repeated infected either viral and bacterial or otherwise.
The low number of blood platelets lead to:
1. The emergence of bruises in any part of the body without any apparent reason.
2. The emergence of spots or small granules red under the skin.
3. Bleeding nose and gum bleeding.
4. To increase the duration of bleeding when wound infection.
Diagnosis of anemia no aplastic anemia Diagnosis
diagnosed to be anemia no aplastic anemia through: Analysis of
1. Complete full blood count: shows a severe shortage in the number of red blood cells and white blood platelets.
2. A sample of bone marrow.
The treatment of anaemia
Ranging the severity of aplastic anemia the degree of simple medium or acute (strong). In acute cases of the disease there is a severe shortage in the preparation of blood cells, which exposes the patient's life at risk and need to enter the hospital immediately because the treatment in such cases would be to transplant bone marrow. Either in simple cases or medium of the disease, there is no need to hospital and is treated in the transfer of blood and the use of medicines.
The main methods of treatment in the following:
1. Blood transfusion
Most patients aplastic anemia needed to transport repeated blood. will involve the transfer of red blood cells or blood platelets or both depending on the situation of the disease. And does not consider the transfer of blood treatment final of the disease is only offset the shortage of blood cells, which is not based bone marrow for producing and therefore controlled of the symptoms of the lack of these cells.
A. Red blood cells: the transfer of red blood cells lead to a rise in the number of blood and therefore disappear symptoms of anemia and fatigue suffered by the patient. and be the choice of a donor match the same blood group with blood group the patient. And continue transferred cells in the blood of the patient for a month or more.
B. Platelets: to be a compilation of blood platelets after it had been separated from the blood of contributor in a certain way and then be given for the patient.
C. White blood cells: In view of the short age white blood cells would be difficult to transfer the patient. It is therefore the patient infection exhibition easily there is nothing in his white blood cells enough to meet any infection he is exposed to.
2. Medicines and discouraging immune system:
In some cases be the use of medicines and discouraging immune system for treatment because it may be the cause of anemia cases no aplastic anemia is a disorder the immune system shall commence in attacking cells in bone marrow. When the use of such medicines based activity by discouraging the immune system does not affect bone marrow and start bone marrow cells new blood.
For instance those medicines anti-cells anti-thymocyte globulin. Thymoglobulin acetate cyclosporine. and be used alongside medicines Corticosteroids.
3. Bone marrow stimulants:
There are some medicines lead to stimulate and the revitalization of bone marrow cells to produce new blood.
4. Bone marrow transplantation:
To be the replacement of bone marrow to patients great marrow another person unhurt (donor). Is to transplant bone marrow is the only option successful in acute cases (strong) of anemia no aplastic anemia . And the proportion of its success more than 50% of cases where the donor is not of the relatives of the patient. And when contributor of relatives of the patient is getting a chance the success of treatment between each 5 cases of the treatment of 4 cases successfully.
In finding appropriate contributor will be the work of the necessary tests to him. and have been exhausted bone marrow to patients using X-rays or chemical medicines. And then the taking of bone marrow from the donor in a manner that surgery. After that to be the introduction of bone marrow in the blood of the patient through intravenous. find themselves moving bone marrow to bone-cavity and then begins in the composition of blood cells through new 3-4 weeks.
And need transplant of bone marrow to stay in hospital for a long time with some drugs that prevent the rejection of the body of the bone marrow transferred to him.
Aplastic Anemia
اعداد
سلام جبار سلمان
مصطفى حاتم فيصل